Abstract Background We conducted a large-scale epidemiological analysis to investigate the associations between systemic inflammation markers and hypertension prevalence.Our aim is to identify potential biomarkers for early detection of hypertension.Methods A cross-sectional study with 119664 individuals from the Straighteners National Health and N
A sampling-based winner determination model and algorithm for logistics service procurement auctions under double uncertainty
Abstract This paper studies the winner determination problem under disruption and demand uncertainty from the perspective of fourth-party logistics platform.To hedge risks brought by double uncertainty, a hybrid mitigation strategy that integrates temporary outsourcing strategy and fortification strategy is developed.With the objective of minimizin
A novel method for rapid and reliable detection of complex vertebral malformation and bovine leukocyte adhesion deficiency in Holstein cattle
Abstract Background Complex vertebral malformation (CVM) and bovine leukocyte adhesion deficiency (BLAD) are two autosomal recessive lethal genetic defects frequently occurring in Holstein cattle, identifiable by single nucleotide polymorphisms.The objective of this study is to develop a rapid and reliable genotyping assay to screen the active Hols
A Metagenomic Meta-analysis Reveals Functional Signatures of Health and Disease in the Human Gut Microbiome
ABSTRACT While recent research indicates that human health is affected by the gut microbiome, the functional mechanisms that underlie host-microbiome interactions remain poorly resolved.Metagenomic clinical studies can address this problem by revealing specific microbial functions that stratify healthy and diseased individuals.To improve our unders